Soacha is a municipality at the far southwestern corner of greater Bogota. Get yourself there because once you’re on Carrera 40 south of Soacha, your departing the congestion and beginning to feel freedom once again. Just outside Soacha, merge right onto El Colegio-El Charquito Road to follow it up the Bogotá River. You will reach the Salto del Tequendama waterfall after just 6 km of ascent. The river is, at least to me, somehow very beautiful at the same time as it is egregiously polluted. There is a great lookout point at the once-hotel-now-museum near the falls.
From the falls, continue weaving through the mountains for 25 km until you reach Mesitas del Colegio. To avoid tolls, take the Viotá-El Colegio Road south to La Paz and from there take the El Colegio-Anapoima Road to Anapoima. This rather than going north at Mesitas del Colegio to cross the Bogotá River ad join Ruta 21 near La Mesa.